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Faculty and Staff

Lisa Nolan, DVM, PhD
Title:Professor and Chair
Department:Veterinary Microbiology & Preventive Medicine
Organization: Iowa State University
College of Veterinary Medicine
Veterinary Microbiology and Preventive Medicine
Address:2178 College of Veterinary Medicine
Ames, IA 50011
Phone:515-294-3534
Fax:515-294-8500
E-mail:lknolan@iastate.edu
Web Site:http://www.vetmed.iastate.e
du/Faculty_staff/Profiles/l
knolan.asp
Emphases:Food Safety (Pre-Harvest)

Research focuses on bacterial diseases of production animals. The long-term goal of one such project is to establish the molecular basis of virulence of avian Escherichia coli, the causative agent of colibacillosis, an economically devastating problem for this country's poultry industry. Other projects use molecular approaches to study the virulence of various E. coli causing disease in cattle and mink and antimicrobial resistance in salmonellae of pigs.

Publications
Multilocus Sequene Typing Lacks the Discriminatory Ability of Pulse field Gel Electrophoresis for Typing Salmonella enterica serovar Typhimurium
Plasmid-linked virulence among avian pathogenic Escherichia coli
DNA Sequence and Comparative Genomics of pAPEC-02-R, an Avian Pathogenic Escherichia coli Transmissible R Plasmid
Characterizing the APEC Pathotype
Comparison of Eschericia coli Isolates Implicated in Human Urinary Tract Infection and Avian Colibacillosis
Multilocus Sequence Typing Lacks the Discriminatory Ability of Pulsed-Field Gel Electrophoresis for Typing Salmonella enterica Serovar Typhimiurium
Spoilage Identification of Beef Using an Electronic Nose System
Acquisition of a large avian pathogenic Escherichia coli plasmid confers lethality to chick embryos and ability to grow in human urine upon an avirulent E. coli recipient
Analysis of a virulence plasmid of avian Escherichia coli
Virulence cluster in avian pathogenic and uropathogenic Escherichia coli
Escherichia coli isolates from human urinary tract infections and avian colibacillosis
Multiple antimicrobial resistance region of a putative virulence plasmid from an Escherichia coli isolate incriminated in avian colibacillosis
Defining an APEC Pathotype
Modular arrangement of a ColV plasmid in an avian Escherichia coli isolate
Multidisciplinary Educational Program in Food Safety
Defining an APEC pathotype: Role of plasmid-located genes
Molecular Typing of Salmonella enterica Serovar Typhimurium by Multilocus Sequence Typing (MLST) and Pulse-Field Gel Electrophoresis (PFGE)
Plasmid-linked virulence among avian pathogenic Escherichia coli
Avian pathogenic Escherichia coli are distinguished from commensal E. coli by the presence of traits associated with large plasmids
Prediction of chicken embryo lethality with the avian Escherichia coli traits complement resistance, Colicin V productin, and presence of increased serum survival gene cluster (iss)
Characterizing avian Escherichia coli isolates with multiplex PCR
Logistic Regression of the Embryo Lethality Assay and correlation of Complement Resistance, iss, and ColV Production with Virulence in Avian Pathogenic Escherichia coli (APECs)
Cloning and Sequence Analysis of cnf-1 from Virulent bovine and Mink Escherichia coli Isolates
Monoclonal Antibodies to Avian Escherichia coli Iss
Characterization of Escherichia coli Isolates Incriminated in Mink Colisepticemia
Serum Complement Resistance, iss, and Virulence of Avian Escherichia coli
Characterization of Multiple-antimicrobial Resistant Salmonella Isolated from Diseased Swine
Complement Resistance, as Determined by Viable Count and Flow Cytometric Methods, and its Association with the Presence of iss and the virulence of Avian Escherichia coli
Location of iss and Selected Traits on a Conjugative R Plasmid in an Avian Escherichia coli Isolate
Virulence Factors of Escherichia coli from Cellulitis or Colisepticemia Lesions in Chickens
Are Escherichia coli isolates from human urinary tract infections and avian colibacillosis the same?
Virulence genotyping of Salmonella spp.
Col V plasmid-linked virulence among Escherichia coli


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  Food Safety Consortium · Iowa State University · Ames, Iowa 50011 · USA · E-mail: foodsafety@iastate.edu